As seen with the sub-title, Chicago, The Presidium is a 'not so original vampire story.'
This is a free form room, which does not ascribe to a specific list of powers or the where and why of how a vampire came into being. Was it a witch that created the first vampire? A demon? An angel. Or just genetics falling at the right, or wrong time.
Have you played VtM and found it mind turning in detail? Or LKH and liked it but....not as much as you thought you would? Have you wanted to play but not be so 'restricted' as to the creation and development of your character?
You're in luck, Chicago is here.
As this is a free-form room, you can play your chars how you wish. With the typical caveat...no god-moding. No killing off another's char without previous agreement. No wanton destruction unless it is a pre-approved room wide (city-wide) storyline where 'everyone' in the city would be affected.
Do you want to play a vampire with a mix of VtM and LKH powers or siring ability? Have at it. Just power list your chars (be they vampire, witch, werewolf, shifter or creepy crawlie).